Kanmin Xue Selected Research

Choroideremia

1/2021	Expression of Rab Prenylation Pathway Genes and Relation to Disease Progression in Choroideremia.
1/2021	Is subretinal AAV gene replacement still the only viable treatment option for choroideremia?
1/2020	Association of Messenger RNA Level With Phenotype in Patients With Choroideremia: Potential Implications for Gene Therapy Dose.
6/2019	A detailed in vivo analysis of the retinal nerve fibre layer in choroideremia.
1/2019	Near-Infrared Autofluorescence in Choroideremia: Anatomic and Functional Correlations.
10/2018	Beneficial effects on vision in patients undergoing retinal gene therapy for choroideremia.
1/2018	Ocular gene therapy for choroideremia: clinical trials and future perspectives.
1/2018	Choroideremia: molecular mechanisms and development of AAV gene therapy.
10/2017	Characterizing the Natural History of Visual Function in Choroideremia Using Microperimetry and Multimodal Retinal Imaging.
3/2017	Structural and Functional Recovery Following Limited Iatrogenic Macular Detachment for Retinal Gene Therapy.

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Kanmin Xue Research Topics

Disease

12	Choroideremia 01/2021 - 01/2016
4	Disease Progression 01/2021 - 01/2020
3	Inflammation (Inflammations) 09/2021 - 01/2020
2	Retinopathy of Prematurity (Retrolental Fibroplasia) 12/2022 - 05/2015
2	Hemorrhage 01/2022 - 05/2015
2	Retinal Degeneration 01/2021 - 11/2020
2	Retinal Diseases 10/2020 - 01/2018
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2020 - 01/2018
2	Capillary Hemangioma 09/2018 - 09/2013
2	Retinal Detachment (Retinal Detachments) 03/2017 - 01/2017
1	Glaucoma 01/2022
1	Neuroinflammatory Diseases 06/2021
1	Alzheimer Disease (Alzheimer's Disease) 06/2021
1	Macular Degeneration (Age-Related Maculopathy) 06/2021
1	Vision Disorders (Hemeralopia) 06/2021
1	Geographic Atrophy 06/2021
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Chronic Renal Insufficiency 01/2021
1	Severe Acute Respiratory Syndrome 07/2020
1	Autoimmune Diseases (Autoimmune Disease) 07/2020
1	Virus Diseases (Viral Diseases) 07/2020
1	Blindness (Hysterical Blindness) 10/2018
1	Fibrosis (Cirrhosis) 09/2018
1	Uveitis 06/2018
1	Cataract (Cataracts) 02/2018
1	Leber Congenital Amaurosis 01/2018
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2018
1	Bietti Crystalline Dystrophy 01/2018
1	Penetrating Eye Injuries 08/2013
1	Aphakia 08/2013

Drug/Important Bio-Agent (IBA)

16	Retinaldehyde (Retinal)IBA 01/2022 - 05/2015
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 03/2017
2	Pharmaceutical PreparationsIBA 01/2022 - 07/2020
2	rab GTP-Binding ProteinsIBA 01/2021 - 01/2018
2	Messenger RNA (mRNA)IBA 10/2020 - 01/2020
2	Timolol (Blocadren)FDA LinkGeneric 09/2018 - 09/2013
1	Ranibizumab (Lucentis)FDA Link 12/2022
1	Bevacizumab (Avastin)FDA Link 12/2022
1	afliberceptIBA 12/2022
1	Amyloid beta-PeptidesIBA 06/2021
1	ApolipoproteinsIBA 06/2021
1	Apolipoproteins E (ApoE)IBA 06/2021
1	Complement System Proteins (Complement)IBA 06/2021
1	Apolipoprotein E4IBA 06/2021
1	Blood Glucose (Blood Sugar)IBA 01/2021
1	Retinal Pigments (Pigments, Visual)IBA 01/2021
1	Antisense OligonucleotidesIBA 10/2020
1	Chloroquine (Aralen)FDA LinkGeneric 07/2020
1	Antimalarials (Antimalarial Agents)IBA 07/2020
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 07/2020
1	Codon (Codons)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	SteroidsIBA 01/2020
1	CollagenIBA 09/2018
1	Biosimilar PharmaceuticalsIBA 06/2018
1	TransferasesIBA 01/2018
1	Hydroxymethylglutaryl CoA Reductases (HMG CoA Reductase)IBA 01/2018
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 01/2018
1	Isoflurophate (DFP)FDA Link 01/2018
1	Rab geranylgeranyltransferaseIBA 01/2018
1	geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA 01/2018
1	Coenzyme A (CoA)IBA 01/2018
1	Nonsense Codon (Nonsense Mutation)IBA 01/2018
1	cytotropic heterogeneous molecular lipid (CHML)IBA 01/2018
1	Rab geranylgeranyl transferase beta-subunitIBA 01/2018
1	geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA 01/2018
1	Green Fluorescent ProteinsIBA 01/2018
1	rho-Associated KinasesIBA 01/2017
1	Cyclopentolate (Cyclogyl)FDA LinkGeneric 05/2015
1	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 05/2015

Therapy/Procedure

7	Therapeutics 12/2022 - 06/2018
2	Lasers (Laser) 12/2022 - 01/2016
1	Retreatment 12/2022
1	Vitreoretinal Surgery 01/2022
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2022
1	Immunomodulation 06/2018
1	Biological Therapy 06/2018
1	Intraocular Lenses (Intraocular Lens) 02/2018
1	Intraocular Lens Implantation 08/2013